Best Probiotics for Infants and Toddlers – May, 2021 Reviews and Top Picks

When you look at your innocent, adorable baby or toddler, you know how strong the urge is to protect, nourish, and care for it. One of the most important things you can do to care for your infant or toddler is to take care regarding what you feed it. While most parents know to feed their children healthy foods, one element often gets overlooked: probiotics.

Probiotics for infants are now considered necessary, thanks to new research that shows that amniotic fluid is not sterile like we once thought it was. The kind of bacteria found in the fluid is shaped by the type of gut flora in the mother. Because of this, if you have less than ideal gut flora (due to things like taking antibiotics, eating white bread or pasta, or not eating enough fermented foods), your child may be in need of probiotics to help them be as healthy as they can be.

Before you give your infant or toddler probiotics, here are useful things to know:

  • Without the right gut flora, your baby may be prone to unpleasant digestive issues, such as diarrhea, constipation, colic, or acid reflux.
  • An infant or toddler without healthy gut bacteria may also be more at risk for developing more serious digestive issues, such as IBS (Irritable Bowel Syndrome) or Crohn’s Disease.
  • It’s vital that you provide the best, safest products for your infant or toddler. Be sure to do adequate research on any given product before administering to your child (that’s where we are here to help!). Also, you can look for products that offer probiotics for infants and toddlers and vitamin c and other nutrients well, to be sure your baby is getting everything they need.
  • Gut bacteria impact more than just digestive issues. The right probiotics can also help improve your baby’s immune system — and even their mood! (And who doesn’t want a happy baby?)

We’ve curated a list of the best probiotics for toddlers and infants, so you can make sure your child is as healthy and happy as they can be.

Best Probiotics for Infants and Toddlers

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Children’s Grape Probonix

A liquid probiotic can be far more natural for an infant or toddler to take; a grape-flavored liquid probiotic can be an absolute breeze. Let your child feel like they have a treat with Children’s Grape Protonix, a candy-flavored liquid that can ease your kid’s digestive issues while making their mouth happy.

Even a child that feels well isn’t going to like to take badly-flavored, hard to swallow supplements, so probiotics for toddlers constipation (or other digestive issues that make them feel awful and cranky) should be exceptionally easy to administer. These drops can be mixed with fresh liquids, so it can be added to flavorful juice for a hydrating, fruit-flavored experience that you can both feel good about.

This also makes Children’s Grape Probonix one of the tremendous liquid probiotics for infants, as it can be added to their bottle and will just be seen as a tastier-version of their already-favorite meal.

Pros and Cons

  • Grape flavor
  • Can be mixed with cold liquids
  • No refrigeration required
  • Some dislike the flavor
  • Some report issues with the applicator

Protectis Baby

Sometimes the original can be the best. Protects Baby is one of the best probiotics for infants on the market thanks to ingredients trusted by pediatricians, as well as shown clinically to work for newborns and toddlers.

When your infant or toddler is faced with diarrhea, colic, constipation, spit-ups, or other stomach upsets (that can break your heart to witness), Protects Baby may be just the thing you need to help get your child feeling like their best self again.

If your sleep has been interrupted by a fussy, crying baby (and nearly every parent has), then Protectis Baby may be the probiotic of you (sought-after) dreams: its formula has been clinically-shown to reducing crying in infants with colic. Sweet dreams, indeed!

Pros and Cons

  • The original probiotic drop for babies
  • Contains vitamins D3
  • A plastic tube is BPA-free
  • Pricey

Culturelle Kids Probiotic

When your child has digestive issues, you’ll want to do all you can to get them feeling better fast (and to avoid the risk of dehydration that can come along with vomiting or bowel issues), and Culturelle Kids Probiotic treats many symptoms that encourage you to try probiotics for toddlers, diarrhea, and digestive problems among them.

You also will want something that is easy for your infant or toddler to take; when they aren’t feeling well, it can be impossible to get them to make something that is difficult for them to swallow or that tastes awful.

Luckily, you can mix Culturelle Kids Probiotic into any non-warm or hot food or beverage. Meaning you can give your child whatever food they can tolerate, that they also love (like juice, pudding, milk, or ice cream) and they’ll get all the health benefits they need—without the stress.

Pros and Cons

  • Dairy-free
  • Can be taken with or without food
  • Tasteless
  • Pricey

Kids Probiotics

Probiotics for toddlers immune system health are vital, and never more so than after they’ve been on a course of antibiotics. To help replenish the healthy, healthy bacteria that antibiotics can destroy, consider giving your child Kids Probiotics, which feature a formula that is ideal for after a course of antibiotics.

These clinically-researched kid-friendly strains also improve overall digestive health, boost their immune system, and may promote healthy brain development. Who doesn’t want to help their child be their happiest, healthiest best?

Toddlers with allergies are likely to do well with Kids Probiotics, as they contain no yeast, lactose (although they may include trace milk proteins), soy, gluten, nuts, wheat, eggs, or artificial colors, flavors, sweeteners, or preservatives.

Pros and Cons

  • Ideal during and after antibiotics
  • Clinically-researched, kid-friendly strains
  • Sugar-Free
  • May contain trace amounts of milk protein
  • May be difficult for young children to swallow

Garden of Life - RAW Probiotics KIds

No parent wants to give their infant something that is impure or that contains harsh, irritating, or unknown ingredients (who can even pronounce half the things in many “health” products on the market today?). That’s why Garden of Life – RAW Probiotics Kids is among the best probiotics for infants and toddlers.

Its gentle formula is vegetarian, contains no binders or fillers, and is full of 23 RAW and organic fruits and vegetables that are chosen specially for their ability to support healthy gut bacteria growth in your child, making these live probiotics for infants full of natural wonders.

Not only that, Garden of Life - RAW Probiotics Kids is gluten-free, certified organic, sugar-free, and contains no soy allergens. You can feel right about what you are giving your infant, and your infant can feel good after taking them!

Pros and Cons

  • Contains no binders or fillers
  • Vegetarian
  • Organic
  • None


It’s no secret that kids usually dislike the taste of medicine. (And really, don’t we adults hate it as well?) That’s why Kidophilus has designed probiotics drops for infants and toddlers that they may want to take.

Featuring a delicious fruit punch flavor, these probiotics are ones you likely won’t have to battle with your child to get them to take (and no parent of an infant or toddler needs that additional stress).

Not only do the ingredients in Kidophilus taste good—they are right. The ingredients are sourced directly from nature, and the drops are manufactured and bottled in a state-of-the-art GMP-certified factory.

Pros and Cons

  • Fruit-punch flavored liquid
  • Manufactured in a GMP-certified facility
  • Low cost
  • Contains preservatives

Baby Grow + Thrive Probiotics + Vitamin D Drops

Feeling unsure about who to trust when it comes to probiotics for your infant or toddler? Baby Grow + Thrive Probiotics + Vitamin D Drops are from the #1 pediatrician recommended the brand, so you can feel confident in your choice, and great about the supplements you’re providing your child.

Containing the most clinically-tested probiotic, as well as designed specifically for babies, this formula is safe, gentle, and helps you build a strong foundation of health for your child. Your infant’s development now may impact their health for the rest of your life; do all you can to guard it and give them the best chance of healthy, happy years in the future.

Grow + Thrive Probiotics + Vitamin D Drops are also sugar-free, gluten-free, and dairy-free, meaning you can feel even better about what you are giving your beloved baby.

Pros and Cons

  • No hidden ingredients
  • Contains the most clinically-tested probiotic
  • Designed specifically for babies
  • A sticky formula may be hard to measure

Mommy’s Bliss Baby Probiotic Drops

If you are not only about the future of your child’s health but the future health of the world itself, you likely are interested in sustainable, eco-friendly options. If so, Mommy’s Bliss Baby Probiotic Drops may be your favorite choice on this list. Not only are they vegan, but they’re made with sustainable ingredients, so they work toward a bright future for your child and the planet they will inhabit.

This pediatrician-recommended liquid formula is also flavorless, making it easy to administer to the pickiest, fussiest infant or toddler. This powerful formula is gentle enough for newborns, so you can feel good about helping to make your infant as healthy as possible from as early on as you can.

Featuring a probiotic strain that has been studied in an astounding over 800 scientific studies, this formula also includes no dairy, gluten, or soy, and is 100% natural with no additives, chemicals, parabens, or artificial colors or flavors. Feel good about making your baby feel good!

Pros and Cons

  • Pediatrician recommended
  • Vegan
  • No additives
  • Must be kept away from humidity and light
  • Some have problems with the dropper

Soothe Probiotic Colic Drops

You’ve never know stress until you’ve identified a colicky baby—and Soothe Probiotic Colic Drops are here to help. Specially designed by trusted-brand Gerber to help ease colic, these drops may help prevent excessive fussiness and crying in your infant, which will make you both happy.

In fact, Soothe Probiotic Colic Drops have been clinically shown to reduce crying time in colicky, breastfed babies by 50% (now those are results that can help you both sleep at night!). Don’t worry, though; these drops are also designed to work well for formula-fed infants.

If your infant is up all night, crying and uncomfortable, these GMO-free drops may be the solution you both have been dreaming about.

Pros and Cons

  • Non GMO
  • Comforting Probiotics
  • #1 Pediatrician Recommended Brand for Colic
  • Ease colic
  • Pricey

Nexabiotic Probiotic Powder for Infants & Toddlers

If you’re anything like me (and let’s face, probably 90% of parents), you’re probably paranoid about getting every dosage of your child’s medications or supplements precisely right. Nexabiotic Probiotic Powder for Infants & Toddlers makes this an absolute breeze. Its powder comes pre-dosed in capsules, so you don’t have to worry about measuring (and remeasuring).

The powder is also flavorless, which means you can mix it with your infant or toddler’s food and they likely won’t even notice you’ve put anything in there! (And some children are resistant to taking a supplement also if they like the taste, so having it be a hidden benefit may be the easiest way to keep your child healthy.)

This advanced formula is powerful enough to help prevent multiple digestive issues potentially, yet is safe and gentle enough to give to your infant. Not only that, it’s made in the USA, so you can feel confident that you are giving your child the best.

Pros and Cons

  • Flavorless
  • Made in the USA
  • Pre-dosed power in capsules
  • Maybe dangerous for immunocompromised children

Final Thoughts

We know your child’s health is the most important thing to you. It’s becoming more evident that the development of gut bacteria in your infant or toddler’s body may not only impact their current health but may affect their health for the rest of their life as well.

These probiotics are our top picks for helping you to help your child be as healthy as possible. Consider adding a probiotic to your infant or toddler’s routine, and see the difference that it can make, both for now and years to come.